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Azhar R Hussain Selected Research

Phosphatidylinositol 3-Kinases (PI 3 Kinase)

9/2017XIAP over-expression is an independent poor prognostic marker in Middle Eastern breast cancer and can be targeted to induce efficient apoptosis.
2/2014Role of dysregulated expression of leptin and leptin receptors in colorectal carcinogenesis.
1/2012Cross-talk between NFkB and the PI3-kinase/AKT pathway can be targeted in primary effusion lymphoma (PEL) cell lines for efficient apoptosis.
1/2011Role of leptin and its receptors in the pathogenesis of thyroid cancer.
1/2011Resveratrol suppresses constitutive activation of AKT via generation of ROS and induces apoptosis in diffuse large B cell lymphoma cell lines.

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Azhar R Hussain Research Topics

Disease

27Neoplasms (Cancer)
09/2017 - 10/2005
9Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
02/2014 - 12/2006
8Colorectal Neoplasms (Colorectal Cancer)
07/2015 - 05/2008
6Primary Effusion Lymphoma
01/2012 - 04/2005
4Lymphoma (Lymphomas)
02/2014 - 10/2008
4Papillary Thyroid Cancer
03/2012 - 10/2008
3Carcinogenesis
02/2014 - 05/2010
2Ovarian Epithelial Carcinoma
05/2015 - 10/2009
2Obesity
02/2014 - 11/2009
2B-Cell Lymphoma (Lymphoma, B Cell)
01/2013 - 01/2012
2Thyroid Neoplasms (Thyroid Cancer)
01/2011 - 01/2011
1Breast Neoplasms (Breast Cancer)
09/2017
1Necrosis
07/2010
1Carcinoma (Carcinomatosis)
11/2009
1Burkitt Lymphoma (Burkitt's Lymphoma)
10/2008
1Kaposi Sarcoma (Kaposi's Sarcoma)
04/2005

Drug/Important Bio-Agent (IBA)

6Phosphotransferases (Kinase)IBA
02/2014 - 05/2010
5Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
09/2017 - 01/2011
5Bortezomib (Velcade)FDA Link
02/2014 - 05/2008
4Leptin ReceptorsIBA
02/2014 - 11/2009
4LeptinIBA
02/2014 - 11/2009
3Proteins (Proteins, Gene)FDA Link
07/2012 - 04/2005
3LigandsIBA
03/2012 - 07/2010
35- ((2,6- dichlorobenzyl)sulfonyl)- 3- ((3,5- dimethyl- 4- ((2- (pyrrolidin- 1- ylmethyl)pyrrolidin- 1- yl)carbonyl)- 1H- pyrrol- 2- yl)methylene)- 1,3- dihydro- 2H- indol- 2- oneIBA
03/2012 - 01/2011
3Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
12/2011 - 09/2010
3Fatty Acid Synthases (Fatty Acid Synthase)IBA
05/2010 - 10/2008
3Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
11/2009 - 04/2005
3Protein Kinases (Protein Kinase)IBA
10/2009 - 05/2008
2embelinIBA
09/2017 - 07/2015
2Cisplatin (Platino)FDA LinkGeneric
05/2015 - 01/2011
2Calcibiotic Root Canal SealerIBA
02/2014 - 11/2009
2thymoquinoneIBA
01/2013 - 04/2011
2Thiostrepton (Gargon)IBA
07/2012 - 01/2012
2Proto-Oncogene Proteins c-metIBA
03/2012 - 01/2011
2X-Linked Inhibitor of Apoptosis ProteinIBA
01/2012 - 10/2010
2TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
12/2011 - 07/2010
2EnzymesIBA
05/2010 - 07/2009
2UbiquitinIBA
10/2009 - 05/2008
2Proteasome Endopeptidase Complex (Proteasome)IBA
10/2009 - 05/2008
2CurcuminIBA
10/2008 - 10/2005
2Phosphatidylinositols (Phosphatidylinositol)IBA
12/2006 - 04/2005
12- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA
09/2017
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
07/2015
1Mechanistic Target of Rapamycin Complex 2IBA
07/2014
1Mechanistic Target of Rapamycin Complex 1IBA
07/2014
1Tumor Biomarkers (Tumor Markers)IBA
07/2012
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2012
1Transcription Factors (Transcription Factor)IBA
01/2012
1Matrix Metalloproteinases (MMPs)IBA
01/2012
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
01/2012
1Biomarkers (Surrogate Marker)IBA
07/2011
1Biological ProductsIBA
07/2011
1Ubiquitin-Conjugating EnzymesIBA
05/2011
1CyclinsIBA
05/2011
1Oxaliplatin (Eloxatin)FDA LinkGeneric
05/2011
1Reactive Oxygen Species (Oxygen Radicals)IBA
04/2011
1ResveratrolIBA
01/2011
1DecitabineFDA Link
01/2011
1Inhibitor of Apoptosis ProteinsIBA
10/2010
1Death Domain ReceptorsIBA
07/2010
1CytokinesIBA
07/2010
1Fatty Acids (Saturated Fatty Acids)IBA
05/2010
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
05/2010
1AdipokinesIBA
11/2009
1Phospholipids (Phosphatides)FDA LinkGeneric
07/2009
1benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA
07/2009
1Proteasome InhibitorsIBA
07/2009
1NF-kappa B (NF-kB)IBA
10/2008
1bcl-2-Associated X Protein (bcl 2 Associated X Protein)IBA
10/2008
1sanguinarineIBA
04/2007

Therapy/Procedure

4Drug Therapy (Chemotherapy)
02/2014 - 04/2007
2Therapeutics
07/2015 - 07/2010